From Atlanta, GA
- Take I-20 East for 207 miles
- Continue past Augusta into South Carolina
- At Columbia, take exit 64A
- Merge into I-26 East
- Continue along I-26 as it becomes I-126, then Elmwood Avenue
- Take a right on Main Street
From Augusta, GA
- Take I-20 East for 66 miles
- At Columbia, take exit 64A
- Merge into I-26 East
- Continue along I-26 as it becomes I-126, then Elmwood Avenue
- Take a right on Main Street
From Charlotte, NC
- Take I-77 South for 81 miles
- Merge onto SC 277 South toward Augusta/I-20
- Continue 8 miles until 277 becomes Bull Street
- Turn right on Gervais Street
From Raleigh, NC
- Take I-40 east for 30 miles
- Take exit 328A and merge onto I-95 South, continue for 119 miles
- Take exit 190B and merge onto I-20 West
- Merge onto SC 277 South toward Augusta/I-20
- Continue 8 miles until 277 becomes Bull Street
- Turn right on Gervais Street
From Asheville, NC
- Take I-240 West for 1.5 miles
- Merge onto I-26 East, continue for 151 miles
- Continue along I-26 as it becomes I-126, then Elmwood Avenue
- Take a right on Gervais Street
From Nashville, TN
- Take I-40 East for 155 miles
- Merge onto I-75 North for 284 miles
- Merge onto US 74 East, continue for .4 miles
- Merge onto I-26 East, continue for 148 miles
- Continue along I-26 as it becomes I-126, then Elmwood Avenue
- Take a right on Main Street
From Savannah, GA
- Take I-95 North for 94 miles
- Take Exit 86B and merge onto I-26 toward Columbia
- Continue for 60 miles then take Exit 108B for I-126/Columbia
- Continue along I-126 as it becomes Elmwood Avenue
- Take a right on Main Street
From Charleston, SC
- Take I-26 West, continue for 112 miles
- Take Exit 108B for I-126/Columbia
- Continue along I-126 as it becomes Elmwood Avenue
- Take a right on Main Street
From Greenville, SC
- Take I-385 South for 42 miles
- Merge onto I-26 East, continue for 56.2 miles
- Continue along I-26 as it becomes I-126 then Elmwood Avenue
- Take a right on Main Street